I bought a Holley 0-80457S (4160) to replace the stock Motorcraft (Holley) on my F250.
I had never worked on a Holley before, worked on Carter’s, now Edelbrock and Quadrajets.
I was surprised at how much I liked it. It’s been easy to tune, replaced jets three times now because initially I went a size lower because of the elevation I live at, 4200 feet. Went back to what came with it and again ordered the next size bigger, because IMHO these 460’s like their fuel.
This carb is not a dual feed so there is a tube between the primary bowl and secondary bowl. Had that leak the first time I replaced the jets, I learned to give that tube a gentle twist back and forth and no problems with that since.
I contacted tech support about jetting and their response was quick and professional.
Edit: the exchange was easy because the linkage hooked right up.