I tried to find a new harness about 3 years ago (a full one) as my wiring was very brittle.
There were no new Ford harnesses and the only kits were generic and used their own (non ford) connectors so would have been even more complicated. I ended up pulling harness out of 2 other trucks I found then, opening up the harnesses (including my original) and cherry picking the best of the 3 wires for each circuit.
I was able to free the wires from most of the plastic multi-pin connectors using an eye-glass repair screw driver to depress the little tab inside the plastic connector that holds the metal connector (crimped on the wire) in place. The new, better wire then just snaps back into the plastic connector. The metal connectors on the wires are available, but I only found them in combination multi packs, which isn't an easy way to get what you want. I opted not to use new wires because I needed more than 7 colors to keep from confusing myself about what wire was which circuit.
There are some connectors, especially outside the firewall (i think the ignition circuits) that are molded so the wires cannot be detached. I used new non-ford waterproof connectors to replace those.